Contact：jiaoning@cpl.ac.cn
Education
1999-2004 Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, PhD
(Supervisor: Professor Shengming Ma)
1995-1999 B.S. Organic Chemistry, Shandong University, Ji’nan, P. R. China
Academic Experience
2010-Present State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Professor
2007- 2010 State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Associate Professor
2004-2006 Max Planck Institute für Kohlenforschung (MPI) Mülheim an der Ruhr, Germany, Postdoctor
(Supervisor：Professor Manfred T. Reetz), Alexander von Humboldt Fellowship Professor
Overview of Academic Research
The research in my group has been focused on the discovery of new strategies and new heteroatom incorporation methodologies towards the efficient and inexpensive synthesis and modification of drugs, natural products, as well as bioactive compounds. Meanwhile, our goal was also to design and discover new drugs for the treatment of metabolic syndrome. We have published >180 papers in Nature, Science，Nat. Chem.，Nat. Catal. and other journals. Some good candidates for the treatment of cancers and diabetes mellitus including nonalcoholic steatohepatitis were identified.
Major Honor and Awards
2021 Xplorer Prizer
2020 the first prize in Natural Science Award of Ministry of Education2019 the first prize in Natural Science Award of Beijing
2017 The National Young and Middle-aged Expert with Remarkable Contributions (by the Ministry of Human Resources and Social Security of China)
2016 The National Young and Middle-aged Leading Science and Technology Innovation Talents (by the National Ministry of Science and Technology)
2015 Yangtze river scholars Distinguished Professor
2015 Fellow of the Royal Society of Chemistry
Representative Research Achievements
1.Jia-Le Wang, Xiao-Dong Dou, Jie Cheng, Ming-Xin Gao, Guo-Feng Xu, Wei Ding, Jin-Hui Ding, Yu Li, Si-Han Wang, Zhao-Wei Ji, Xin-Yi Zhao, Tong-Yu Huo, Cai-Fang Zhang, Ya-Meng Liu, Xue-Ying Sha, Jia-Rui Gao, Wen-Hui Zhang, Cheng Zhang, Xiao Yu*, Ning Jiao*, Jin-Peng Sun*. From target identification to a therapeutic lead, functional screening- and rational design of compounds targeting GPR132 to treat diabetes. Nature Metabolism, in revision.
2. Xu Qiu, Yueqian Sang, Hao Wu, Xiao-Song Xue, Zixi Yan, Yachong Wang, Zengrui Cheng, Xiaoyang Wang, Hui Tan, Song Song, Guisheng Zhang, Xiaohui Zhang, K. N. Houk*, and Ning Jiao*. Cleaving arene rings for acyclic alkenylnitrile synthesis. Nature, 2021, 597: 64-69.
3. Yujie Liang, Shihui Shi, Rui Jin, Xu Qiu, Jialiang Wei, Hui Tan, Xue Jiang, Xiaomeng Shi, Song Song, and Ning Jiao*. Electrochemically induced nickel catalysis for oxygenation reactions with water. Nat. Catal., 2021, 4: 116-123.
4. Jianzhong Liu, Cheng Zhang, Ziyao Zhang, Xiaojin Wen, Xiaodong Dou, Jialiang Wei, Xu Qiu, Song Song, and Ning Jiao*. Nitromethane as a nitrogen donor in Schmidt-type formation of amides and nitriles. Science, 2020, 367: 281-285.
5. Song Song, Xinyao Li, Jialiang Wei, Weijin Wang, Yiqun Zhang, Lingsheng Ai, Yuchao Zhu, Xiaomeng Shi, Xiaohui Zhang and Ning Jiao*. DMSO-Catalyzed Late-Stage Chlorination of (Hetero)Arenes. Nat. Catal. , 2020, 3: 107-115.
6. Jianzhong Liu, Xu Qiu, Xiaoqiang Huang, Xiao Luo, Jialiang Wei, Jun Pan, Yujie Liang, Yuchao Zhu, Qixue Qin, Song Song, and Ning Jiao*. From Alkylarenes to Anilines via Site-Directed Carbon-Carbon Amination. Nat. Chem., 2019, 11: 71-77.
7. Jun Pan, Xinyao Li, Fengguirong Lin, Jianzhong Liu, Ning Jiao*. Chemoselective Nitrosylation of Anilines and Alkynes via Fragmentary or Complete ‘NO’ Incorporation. Chem., 2018, 4: 1427-1442.
8. Yuchao Zhu, Kaimeng Hunag, Jun Pan, Xu Qiu, Xiao Luo, Qixue Qin, Jialiang Wei, Xiaojin Wen, Lizhi Zhang, and Ning Jiao*. Silver-Catalyzed Remote Csp3-H Functionalization of Aliphatic Alcohols. Nature Commun., 2018, 9: 2625.
9. Yu-Feng Liang, and Ning Jiao*. Oxygenation via C‒H/C‒C Bond Activation with Molecular Oxygen. Acc. Chem. Res., 2017, 50: 1640-1653 (Invited).
